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短程化疗是近几年肺结核治疗的重要进展,至今尚无儿童6个月治疗方案结果的报告本。文探讨儿童肺结核每日服异烟肼(INH)—利福平(RFP)6个月的疗效。对象与方法1979年7月～1988年12月诊断儿童肺结核152例,其中117例按本方案治疗。诊断依据:凡X线检查证明有肺实变或纵隔淋巴结肿大,并具备以下二项或二项以上者:(1)有肺结核的临床症状和体征;(2)有成人肺结核密切接触史;(3)无BCG接种史者结核菌素阳性(PPD≥5mm);(4)痰或胃液抗酸染色阳性或组织学检查发现肉芽肿。治疗方法:INH10mg/kg/d,RFP15mg/kg/d,最大剂
Short-course chemotherapy is an important progress in the treatment of tuberculosis in recent years, so far there is no report on the results of 6-month treatment of children. To investigate the efficacy of daily isoniazid (INH) - rifampicin (RFP) for 6 months in children with pulmonary tuberculosis. Subjects and methods July 1979 ~ December 1988 diagnosis of 152 cases of tuberculosis in children, of which 117 cases were treated according to the program. Diagnosis is based on: X-ray examination showed pulmonary consolidation or mediastinal lymph nodes and have the following two or more: (1) the clinical symptoms and signs of tuberculosis; (2) the history of close contact with adult tuberculosis; (3) tuberculin-positive without BCG inoculation history (PPD≥5mm); (4) sputum or gastric acid-positive staining or histological examination found granuloma. Treatment: INH10mg / kg / d, RFP15mg / kg / d, the maximum dose