目的 :研究以强直症状为主的帕金森病 (PD)患者脊髓α运动神经元的兴奋性是否增高。方法 :选取一组以强直症状为主的PD患者与一组年龄、性别匹配的正常人作对照研究 ,分别测定其静息、易化状态时的F波 ,并进行比较。结果 :以强直症状为主的帕金森病患者F波多项参数增加 ,易化现象明显受损。结论 :以强直症状为主的帕金森病患者脊髓α运动神经元的兴奋性有增高 OBJECTIVE: To investigate whether the excitability of spinal motor neurons in the Parkinson’s disease (PD) predominantly characterized by rigidity is increased. Methods: A group of patients with PD predominantly characterized by tetanic symptoms were selected and compared with a group of normal subjects of age and sex matched. The F wave at rest and facilitated state were measured and compared. Results: F-wave multinomial parameters of Parkinson’s disease dominated by tetanic symptoms increased significantly and facilitation was significantly impaired. CONCLUSIONS: The excitability of spinal motor neurons in Parkinson’s disease, predominantly tetanus, is increased