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目的分析重型颅脑损伤患者应用营养支持对营养指标和肺部感染的影响。方法资料随机选自2013年3月-2014年3月本院诊治的重型颅脑损伤患者96例,按照完全抽样法1∶1分成两组,对照组予肠外营养支持治疗,研究组予肠内营养支持治疗,比较两组患者治疗后的疗效性、综合性与安全性指标情况。结果研究组治疗d 15的ALB水平(38.64±1.86)g/L、PA水平(0.18±0.05)g/L均比对照组(32.64±2.36)g/L、(0.13±0.02)g/L高,有统计学意义(P<0.05);研究组治疗后d 15的GPT与CRP水平均比对照组低,ICU住院时间与抗菌药物使用天数比对照组短,APACHEⅡ评分比对照组高,差异有统计学意义(P<0.01);研究组患者的恶心呕吐与肺部感染发生率4.17%、10.42%均比对照组27.08%、31.25%低,差异有统计学意义(P<0.01)。结论重型颅脑损伤应用肠内营养支持可明显改善机体营养状况,降低肺部感染的发生风险,利于患者良好预后。
Objective To analyze the effect of nutritional support on nutritional indicators and pulmonary infection in patients with severe craniocerebral injury. Methods Data were randomly selected from 96 patients with severe craniocerebral injury treated in our hospital from March 2013 to March 2014. The patients were divided into two groups according to 1: 1 of the complete sampling method. The control group was given parenteral nutrition support. The study group was given intestine Endovascular supportive therapy was used to compare the efficacy, comprehensiveness and safety of the two groups after treatment. Results The ALB level (38.64 ± 1.86) g / L and PA level (0.18 ± 0.05) g / L in the study group at d 15 were significantly higher than those in the control group (32.64 ± 2.36 g / L and 0.13 ± 0.02 g / L, respectively) (P <0.05). The GPT and CRP levels in study group after d 15 were lower than those in control group. The length of ICU stay and antimicrobial use were shorter than those in control group. APACHEⅡscore was higher than that in control group (P <0.01). The incidences of nausea and vomiting and pulmonary infection in study group were 4.17% and 10.42%, respectively, which were significantly lower than those in control group (27.08% and 31.25%, P <0.01). Conclusion Severe head injury with enteral nutrition support can significantly improve the nutritional status of the body and reduce the risk of lung infection, which will benefit the patients with good prognosis.