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目的 通过对淋巴瘤患者自体外周血干细胞移植 (APSCT)前后外周血象的观察 ,了解移植前后患者的骨髓抑制情况 ,为临床制定合理的治疗方案提供依据。方法 用CEAC(CTX +VP16+ARA -C +CCUN)方案预处理 3例淋巴瘤患者后进行APSCT ,移植前后每天跟踪作血常规检查 ,观察并进行分析。结果 化疗开始后至第 14～ 15天血象持续走低 ,自体干细胞移植后第 6～ 12天后开始回升。结论 (1)动员化疗和预处理化疗 2～ 3周骨髓受到抑制 ,应注意感染和出血的发生。 (2 )预处理后采用集落刺激因子 (G -CSF)将缩短细胞回升的天数
Objective To observe the peripheral blood of peripheral blood stem cells before and after autologous peripheral blood stem cell transplantation (APSCT) in patients with lymphoma to understand the situation of myelosuppression in patients before and after transplantation, and to provide the basis for establishing a reasonable treatment plan. Methods Three patients with lymphoma were pretreated with CEAC (CTX + VP16 + ARA-C + CCUN) for APSCT. Blood samples were routinely inspected before and after transplantation for observation and analysis. Results After the start of chemotherapy, the blood picture continued to decrease from the 14th to the 15th day, and started to recover after 6 to 12 days after autologous stem cell transplantation. Conclusion (1) mobilization chemotherapy and pretreatment 2 to 3 weeks after bone marrow suppression, should pay attention to the occurrence of infection and bleeding. (2) The number of days after cell pre-treatment using colony stimulating factor (G-CSF)