胰腺平滑肌肉瘤是一种极少见的胰腺间叶组织恶性肿瘤,至今文献仅查见4例临床个案报告。本文报告1例伴有巨大假性胰腺囊肿。患者男,55岁,因左上腹包块1月余,腰背部疼痛并进行性消瘦入院。3个月前曾有上消化道大出血史,无其他疾病史。查体:患者呈恶病质状态。 Pancreatic leiomyosarcoma is a rare malignant tumor of the pancreatic mesenchymal tissue. To date, only 4 clinical cases have been reported in the literature. This article reports 1 case with a huge pseudo-pancreatic cyst. The patient was male, 55 years old, admitted to the hospital with left upper quadrant mass more than 1 month, low back pain and progressive weight loss. There was a history of major bleeding in the upper digestive tract 3 months earlier and no history of other diseases. Physical examination: The patient was in a cachexia condition.