1942年Jaffe和Lichtenstein首次报道软骨母细胞瘤是一种少见的特殊类型骨肿瘤,把它和骨巨细胞瘤分开。截止1985年,英文文献约有800余例报道。本文报道18例软骨母细胞瘤的临床、病理、免疫组织化学及超微结构观察。1 材料和方法我们自1970～1992年共收集软骨母细胞瘤18例(外单位4例)。1.1 光镜检查材料制备18例活检组织用10%福尔马林固定、石 In 1942, Jaffe and Lichtenstein first reported that chondroblastoma is a rare, special type of bone tumor that separates it from giant cell tumor of bone. As of 1985, there were more than 800 reports of English literature. This article reported the clinical, pathological, immunohistochemical and ultrastructural observations of 18 cases of chondroblastoma. 1 Materials and Methods We collected 18 cases of chondroblastoma from 1970 to 1992 (outpatient 4 cases). 1.1 Light microscopy material preparation 18 cases of biopsy tissue fixed with 10% formalin, stone