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本文报道了我院1973～1985年间收集的19例成人小脑髓母细胞瘤。男13例,女6例,年龄为16～35岁,平均23.5岁。病程20天～18月,大多数病例病程在2个月以上。 肿瘤位于蚓部15例(80％),小脑半球4例(20％)。7例全切除,11例部分切除,1例活检。11例术后放疗,其中1例同时配合化疗,结果生存3年者2例,5年5例,10年1例,3例不详。另5例术后未放疗,1年内死亡。 虽然髓母细胞瘤尚缺乏使其永久生存的有效方法,当前可以接受的仍然是早期手术和及时放疗。我们强调完全切除肿瘤,即使部分切除,至少也应使脑脊液循环恢复到最佳状态。术后放疗愈早愈好,照射范围应包括全脑和全脊髓。
This article reports 19 cases of adult human cerebellar medulloblastoma collected in our hospital from 1973 to 1985. 13 males and 6 females, aged from 16 to 35 years old, with an average of 23.5 years old. Course of 20 days to 18 months, most cases in more than 2 months duration. The tumor was located in 15 cases (80%) of the vermis and 4 cases (20%) of the cerebellar hemisphere. Total resection in 7 cases, partial resection in 11 cases, biopsy in 1 case. Eleven patients underwent postoperative radiotherapy. One patient was treated with chemotherapy at the same time. Two patients survived for 3 years, 5 patients 5 years and 1 patient 10 years, 3 cases were unknown. The other 5 patients did not radiotherapy, died within 1 year. Although medulloblastoma is still lack of an effective method to make it survive forever, it is still acceptable for early surgery and timely radiotherapy. We emphasize the complete removal of the tumor, even if the partial resection, at least the CSF should be restored to its best circulation. The sooner the better the postoperative radiotherapy, the irradiation range should include whole brain and whole spinal cord.