人类组织激肽释放酶14属于人类组织激肽释放酶家族中的一员,由人类组织激肽释放酶基因14编码,定位于人类染色体19q13.3-13.4上,受甾体类激素调节,其功能可能有降解胶原IV等细胞外基质作用,但具体尚不十分清楚。部分研究表明人类组织激肽释放酶基因14与卵巢癌的生长、转移和浸润有关,对卵巢癌的早期诊断、临床监测和判断预后具有一定价值。 Human Tissue Kallikrein 14, a member of the kallikrein family of human tissues, is encoded by the human tissue kallikrein gene 14 and is located on human chromosome 19q13.3-13.4 and is regulated by steroid hormones which Function may have degraded Collagen IV and other extracellular matrix role, but the specific is not yet clear. Some studies have shown that human tissue kallikrein gene 14 is associated with the growth, metastasis and invasion of ovarian cancer, and is of value in the early diagnosis, clinical monitoring and prognosis of ovarian cancer.