该文报道了2例幼儿感染大肠杆菌O157的病例,其中1例发生溶血性尿毒症综合征,2例都曾在患病前1周与农场家畜有过接触。 一个2岁男孩于发病前9天随父母来到某农场后,出现严重的血样腹泻、呕吐和胃痛等症状。几天后痊愈,无并发症。从患儿的1份粪样中分离到产毒性大肠杆菌(VTEC)O157噬菌体2型(PT2)和产生内毒素的2型(VT2)。在农场逗留的7天中,该患儿喝的是由农场供应的未经处理的牛奶,并与农场的1只幼犬有过密切的接触。据推测患儿与农场家畜(牛、小牛和马)的粪便等排泄物也有直接接触。采集了有60头奶牛的牛群中的牛奶标本,以每3份样本一组,加 This paper reports two cases of early childhood infection of E. coli O157, including 1 case of hemolytic uremic syndrome, and 2 cases had had contact with farm animals 1 week before the illness. A 2-year-old boy developed symptoms of severe blood-borne diarrhea, vomiting and stomachache following her parents’ arrival at a farm 9 days before the onset of illness. A few days later, no complications. Toxicogenic E. coli (VTEC) O157 phage 2 (PT2) and endotoxin producing type 2 (VT2) were isolated from 1 fecal sample of children. During the 7 days of stay on the farm, the child drank untreated milk from the farm and had close contact with a farm puppy. It is estimated that there is also direct contact with the faeces and other excrements in children with farm animals (cattle, calves and horses). Milk samples from a herd of 60 cows were collected, in groups of 3, plus