采用ＭＴＴ法检测６６例患者白血病细胞的药敏，同时采用单抗ＪＳＢ－１，检测白血病细胞Ｐ－１７０的表达，结果表明：Ｐ－１７０表达阳性组药物敏感程度明显低于阴性组（Ｐ＜０．０５）。化疗后Ｐ－１７０表达阳性３６例，其中３２例临床疗效差；１８例Ｐ－１７０表达阴性，其中１３例疗效好。上述结果表明：白血病细胞体外药敏和Ｐ－１７０表达与临床疗效有较好的相关性，总符合率达８３．３％。提示两者同时检测，可更好地指导临床用药。 The sensitivity of 66 cases of leukemia cells was detected by MTT assay, and the expression of P-170 in leukemia cells was detected by the monoclonal antibody JSB-1. The results showed that the sensitivity of the P-170 positive group was significantly lower than that of the negative group (P < 0.05). 36 cases were positive for P-170 after chemotherapy, of which 32 cases had poor clinical curative effect; 18 cases had negative P-170 expression, of which 13 cases were effective. The above results show that: in vitro leukemia drug sensitivity and P-170 expression and clinical efficacy have a good correlation, the total coincidence rate of 83.3%. Prompt detection of both at the same time, can better guide the clinical medication.