帕金森病(Parkinson`s disease,PD)又称“震颤麻痹”,英国医生James Parkinson于1817年首次报道,该病是一种发生于中年以上的黑质和黑质纹状体多巴胺能神经通路变性疾病,是一种常见病、慢性病,临床上以静止性震颤、肌强直、运动迟缓和姿势调节障碍为主要特征。患者男性多于女性。其发病率可随年龄的增加而提高。55～65岁的人群中,帕金森病的发病率为0·3/1000,在年龄≥85岁时,发病率上升为4·4/1000[1]。 Parkinson’s disease (PD), also known as “Parkinson’s disease,” was first reported by British physician James Parkinson in 1817 as a form of dopaminergic neurotoxicity that occurs in the substantia nigra and nigrostriatal striatum over middle age Pathway degenerative diseases, is a common disease, chronic diseases, clinically resting tremor, muscle rigidity, movement retardation and posture adjustment disorders as the main feature. Patients are more males than females. Its incidence can increase with age. The incidence of Parkinson’s disease was 0.3 / 1000 in the 55- to 65-year-old population and 4.4 / 1000 at the age of 85 years.