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目的探讨七氟烷吸入麻醉在消化道肿瘤手术中的应用效果,并分析对不同年龄段患者血液流变学、苏醒时间的影响。方法选取本院2013年1月至2014年12月收治的70例消化道肿瘤手术患者,按照年龄段分为对照组(年龄≤65岁)和老年组(年龄>65岁),两组均给予七氟烷吸入麻醉,对两组患者麻醉情况对比。结果与T1比较,对照组T2点、T3点Hηb、Lηb、Mηb、ηP均明显的降低,T3点ηr降低;与T1比较,老年组T2点、T3点Lηb、Mηb、ηP均明显的降低,T2点ηr降低。与对照组比较,老年组T3点Hηb升高,T2点和T3点ηP也升高,T4点Mηb升高,差异有统计学意义(P<0.05)。老年组EDI明显升高,且维持到术后,T3和T4点两组EDI比较差异显著(P<0.05)。≤两组T3点ERI下降(P<0.05);老年组患者苏醒时间为(12.2±2.1)min,对照组患者苏醒时间为(15.2±2.2)min,差异有统计学意义(P<0.05)。结论应用七氟烷吸入麻醉对降低消化道肿瘤患者血液流变学具有重要作用,尤其年龄在65岁以上老年消化道肿瘤患者快速恢复苏醒,提高麻醉效果。
Objective To investigate the effect of sevoflurane inhalation anesthesia in gastrointestinal cancer surgery and to analyze the effect on hemorrheology and recovery time in patients of different ages. Methods Seventy patients with gastrointestinal cancer admitted from January 2013 to December 2014 in our hospital were divided into control group (≤65 years old) and elderly group (≥65 years old) according to age group, both groups were given Sevoflurane inhalation anesthesia, anesthesia in two groups of patients compared. Results Compared with T1, Hηb, Lηb, Mηb, ηP in T2 and T3 of control group were significantly decreased and ηr of T3 were decreased. Compared with T1, Lηb, Mηb and ηP in T2 and T3 of elderly group were significantly decreased, T2 point ηr decreased. Compared with the control group, the Hηb level of T3 in elderly group increased, ηP increased at T2 and T3, and Mηb increased at T4 (P <0.05). The EDI in the elderly group was significantly higher than that in the control group (P <0.05). ≤ The ERI of both groups decreased (P <0.05). The recovery time of the elderly group was (12.2 ± 2.1) min and that of the control group was (15.2 ± 2.2) min, the difference was statistically significant (P <0.05). Conclusion Sevoflurane inhalation anesthesia plays an important role in reducing hemorrheology in patients with gastrointestinal cancer, especially in elderly patients with gastrointestinal cancer more than 65 years old, recovering quickly and improving anesthesia.