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对32例合并颅内出血的白血病的临床特点、经过进行了回顾性分析,认为周围血小板<50.0×10~9/L,白细胞>50.0×10~9/L 是颅内出血的重要标志。就诊晚、病情重而失去充分化疗机会,或对所用化疗药物不敏感又未及时更换有效的化疗方案是增加颅内出血危险性的不可忽视因素之一,并提出了相应的预防措施。发生颅内出血后,除降颅压,应用常规止血药外,应积极输注血小板和冷冻新鲜血浆。
The clinical features of 32 patients with intracranial hemorrhage leukemia were retrospectively analyzed. It was considered that the peripheral platelets were less than 50.0 × 10 ~ 9 / L and the white blood cells> 50.0 × 10 ~ 9 / L were the important markers of intracranial hemorrhage. It is one of the indispensable factors to increase the risk of intracranial hemorrhage and provide corresponding preventive measures because late treatment, heavy illness and loss of sufficient chemotherapy opportunities, or insensitivity to the chemotherapy drugs used and timely replacement of effective chemotherapy regimens are not negligible. After intracranial hemorrhage, in addition to reducing intracranial pressure, the application of conventional hemostatic drugs, should be actively transfused platelets and frozen fresh plasma.