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探讨肝硬化形成的原因 ,肝硬化病理改变能否逆转和肝硬化病因治疗。任选经临床和病理检查确诊的肝硬化 (早期和代偿期 )病例 70例 ,肌注八八乙肝泰 ,同时观察临床症状和肝功能变化 ,重复肝活检。治后72 9%可获自觉症状消退和肝功能正常 ,11 4%基本正常 ,14 3 %进步 ,肝活检复查早期肝硬化病理特征 6 1 9%消退 ,33 3 %进步 ;代偿期肝硬化假小叶 71 4%消退 ,2 8 6 %进步。肝硬化的治疗原则仍在于有效控制消退肝内慢性炎症 ,确切有效的消退肝内炎症药物可以有效的治疗肝硬化 ,逆转其病理变化 ,因而肝硬化是可以防治的。
To investigate the causes of cirrhosis, liver cirrhosis can reverse the pathological changes and the cause of cirrhosis treatment. Seventy patients with cirrhosis (early stage and decompensated stage) confirmed by clinical and pathological examination were selected and intramuscularly injected with HBeAg. Clinical symptoms and changes of liver function were observed at the same time, and liver biopsy was repeated. 72 9% of the patients received subsided symptoms and normal liver function, 11 4% were basically normal, 14 3% were improved, and liver biopsy was performed. Pathological features of early cirrhosis 6 1 9% regression and 33 3% improvement; compensated cirrhosis False leaflets 71 4% subsided, 286% progress. The principle of the treatment of cirrhosis is still effective in the control of chronic inflammation of the liver subsided, the exact effective elimination of intrahepatic inflammatory drugs can effectively treat cirrhosis and reverse the pathological changes, which can prevent cirrhosis.