论文部分内容阅读
目的探讨巴州结核病的耐药情况。方法随机选取2015年10月~2016年10月各县市定点医院收治的结核病患者180例,对其临床用药资料进行回顾性研究。180例患者均采用痰样本进行耐药性实验,主要研究的药物为异烟肼、利福平、乙胺丁醇以及链霉素。结果 180例患者中有47例出现耐药,耐药率为26.1%;四种药物中异烟肼的耐药率最高,为13.9%,其次是利福平,为8.3%;城镇居民对乙胺丁醇的耐药性明显高于农村居民(P<0.05),其他三种药物的耐药性没有明显差异(P>0.05)结论结核病对四种基本药物的耐药性较高,结核病的防控工作仍然需要强化。对于初发的结核病患者一定要进行积极管理和治疗,从而降低结核病的耐药病例。
Objective To investigate the resistance of tuberculosis in Bavaria. Methods A total of 180 tuberculosis patients admitted to designated hospitals in cities and counties from October 2015 to October 2016 were randomly selected and their clinical data were retrospectively analyzed. 180 patients were sputum samples for drug resistance experiments, the main study drugs are isoniazid, rifampicin, ethambutol and streptomycin. Results Of the 180 patients, 47 cases showed drug resistance with a resistance rate of 26.1%. The drug resistance rate of isoniazid among the four drugs was the highest (13.9%), followed by rifampin (8.3%). Residents in urban areas Drug resistance of melamine butanol was significantly higher than that of rural residents (P <0.05). There was no significant difference in drug resistance among the other three drugs (P> 0.05). Conclusion The drug resistance of tuberculosis to four kinds of essential drugs is high, Prevention and control still need to be strengthened. For newly diagnosed TB patients must be actively managed and treated, thus reducing the number of TB resistant cases.