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肝门部胆管癌,是指左、右主肝管及其汇合部和肝总管上部的恶性肿瘤,亦称上部胆管癌,或称 Klatzkin’s 肿瘤。系肝外胆管癌的好发部位之一。由于临床医生对此病认识不足,常延误诊断治疗,加以癌本身具有浸润性生长,纤维组织多等特点,组织学有时也难以确诊。向邻近肝实质、肝动脉及门静脉侵犯,并沿胆管向肝内扩展,最后常导致手术无法切除,因而,疗效多不满意。近年来,虽然新诊断技术相继使用,早期诊断及疗效较前有所改善,但如何更进一步提高早期诊断率、切除率和生存率,仍是当前肝胆外科中极待解决的课题之一。【发病率】尸体解剖发现肝外胆管癌的发病率为0.01～0.85%。约33%发生于胆总管,20%在胆囊管与肝总管汇合部,25%在肝总管上部,10%位
Hilar cholangiocarcinoma is a malignant tumor of the left and right main hepatic ducts and its confluence and upper hepatic duct. It is also called upper cholangiocarcinoma, or Klatzkin’s tumor. Department of extrahepatic bile duct cancer is one of the most prevalent sites. Due to lack of understanding of the disease, the clinician often delays diagnosis and treatment. The cancer itself has infiltrating growth, many fibrous tissues, and sometimes histological diagnosis is difficult. To the adjacent liver parenchyma, hepatic artery and portal vein invasion, and along the bile duct to the liver expansion, and finally often lead to surgery can not be removed, so the efficacy is not satisfied. In recent years, although new diagnostic techniques have been used in succession, early diagnosis and curative effect have been improved, but how to further improve the early diagnosis rate, resection rate and survival rate is still one of the topics to be solved in the current hepatobiliary surgery. [incidence] The incidence of extrahepatic cholangiocarcinoma was 0.01 to 0.85%. About 33% occurred in the common bile duct, 20% in the confluent part of the cystic duct and hepatic duct, 25% in the upper part of the hepatic duct, and 10%