林肯霉素、氯林肯霉素对革兰氏阳性菌、厌气菌具有较强的抗菌作用,而且体内分布广、可进入骨组织之中。目前多用于骨髓炎、败血症、呼吸系统、肠胃道、五官及软组织感染的治疗,而且产量逐年增长。然而使用林肯霉素、氯林肯霉素时,少数病例可引起假膜性结肠炎而导致死亡。用万古霉素治疗林肯霉素、氯林肯霉素引起的继发性结肠炎是有效的,但是英国Harrow临床研究中心H.E.Larson博士认为,口服万古霉素对严重的抗生素继发性结肠炎虽然有效,但一旦停药,又有发生结肠炎的危 Lincomycin, clindamycin on Gram-positive bacteria, anaerobic bacteria have a strong antibacterial effect, but also widely distributed in the body, can enter the bone tissue. Currently used for the treatment of osteomyelitis, sepsis, respiratory system, gastrointestinal tract, facial features and soft tissue infections, and the annual output growth. However, the use of Lincomycin, clindamycin, a small number of cases can cause pseudomembranous colitis and cause death. Vancomycin treatment of lincomycin, clindamycin-induced secondary colitis is effective, but the United Kingdom Harrow Clinical Research Center Dr HELarson that oral vancomycin is effective for severe antibiotic secondary colitis , But once the withdrawal, there is the risk of colitis