角膜营养不良是一组原发性、遗传性疾病。现代分子遗传学研究的发展使我们对角膜营养不良的认识产生了深远的影响,其在角膜营养不良的诊治中发挥了越来越重要的作用。角膜营养不良的基因研究可使我们从分子水平探讨其发病机理,明确角膜营养不良的诊断和分类。本文概述了近年来我国角膜营养不良分子遗传学的研究状况。 Corneal dystrophy is a group of primary, hereditary diseases. The development of modern molecular genetics makes us have a profound impact on the understanding of corneal malnutrition, which plays an increasingly important role in the diagnosis and treatment of corneal dystrophy. Corneal dystrophy gene research allows us to explore its molecular pathogenesis, clear corneal dystrophy diagnosis and classification. This article summarizes the research status of molecular genetics of corneal malnutrition in China in recent years.