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静脉内吸毒者(IVDUs)为感染GBV-C/HGV(以下统称为HGV)的高危人群,作者对一组药物成瘾妇女中HGV的母婴传播情况进行了研究,并对感染HGV的婴儿进行了随访观察。 研究对象为28例抗-HCV阳性母亲及其所生的29例婴儿。28例母亲中,25例有吸毒史,1例合并HIV-1感染,其余3例在妊娠前数年行肾移植术。所有婴儿均经产道生产,母乳喂养,无输血及血制品史,出生后随访2～12个月,留取不同时间血清标本。所有血清标本均进行抗-HCV、HGV RNA、HCV RNA及ALT检测。抗-HCV的检测采用第2代
Intravenous drug users (IVDUs) are at-risk populations of GBV-C / HGV (hereinafter collectively referred to as HGV). The authors investigated the mother-to-child transmission of HGV in a group of drug-addicted women and evaluated infants infected with HGV Follow-up observation. The subjects were 28 anti-HCV positive mothers and 29 infants born to them. Of the 28 mothers, 25 had a history of drug abuse, 1 had HIV-1 infection, and the remaining 3 had kidney transplantation several years prior to pregnancy. All infants were born through the birth canal, breastfeeding, no history of blood transfusion and blood products, followed up for 2 to 12 months after birth, serum samples taken for different periods. All serum samples were tested for anti-HCV, HGV RNA, HCV RNA and ALT. Anti-HCV test using the second generation