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目的观察足三里穴烫熨对老年结直肠癌患者开腹术后肠道功能的影响。方法将72例65岁以上结直肠癌术后患者随机分为治疗组和对照组(各36例),在足三里穴分别给予烫熨治疗贴和安慰贴,疗程3天。观察患者术后肠鸣音恢复时间及首次排气、排便时间,检测治疗前后血清IL-2、IL-6、NK、CD4+/CD8+水平变化情况。结果 1治疗组术后肠鸣音恢复、首次排气和排便时间短于对照组(P<0.01);2治疗后,治疗组IL-2、CD4+/CD8+水平较治疗前升高(P<0.01),IL-6水平较治疗前降低(P<0.01);两组IL-6和CD4+/CD8+水平比较有统计学差异(P<0.01)。结论足三里穴烫熨治疗能够促进老年结直肠癌开腹术后患者肠道功能恢复,其机制可能与调节炎症反应和免疫功能有关。
Objective To observe the effect of ironing in Zusanli acupoint on intestinal function in elderly patients with colorectal cancer after laparotomy. Methods A total of 72 patients with colorectal cancer over the age of 65 were randomly divided into treatment group and control group (36 cases each), and were treated with hot ironing and comfort paste at Zusanli point for 3 days respectively. The duration of bowel sounds recovery and the time of the first excretion and defecation were observed. The changes of serum IL-2, IL-6, NK and CD4 + / CD8 + levels before and after treatment were observed. Results After treatment, the bowel sounds recovered, the first time of exhaust and defecation was shorter than that of the control group (P <0.01); After treatment, the levels of IL-2 and CD4 + / CD8 + in the treatment group were significantly increased (P <0.01). The levels of IL-6 and CD4 + / CD8 + in the two groups were significantly different (P <0.01). Conclusion Zusanli acupuncture can promote intestinal function recovery in elderly patients with colorectal cancer after laparotomy. The mechanism may be related to the regulation of inflammatory reaction and immune function.