论文部分内容阅读
目的:观察沐舒坦联合沙丁胺醇雾化吸入治疗慢性支气管炎急性发作的临床效果。方法:选取120例慢性支气管炎急性发作患者为研究对象,将其随机分为观察组和对照组各60例。两组均给予常规治疗,在此基础上,对照组给予雾化吸入沙丁胺醇治疗,观察组给予沐舒坦联合沙丁胺醇雾化吸入治疗,7天为1个疗程,治疗后观察对比两组的临床疗效、动脉血气分析结果、通气功能改善情况。结果:治疗后两组患者的症状均得到改善,观察组的总有效率(80.0%)显著高于对照组(60.0%),差异有统计学意义(P<0.05);治疗后两组患者咳嗽、咳痰、气喘症状改善情况比较有显著性差异(P<0.05),呼吸困难症状改善情况比较虽无显著性差异(P>0.05),但观察组较对照组改善更明显;观察组1秒钟用力呼气容积(PEV1)改善情况显著优于对照组(P<0.05),观察组通气/血流(V/Q)改善情况显著优于对照组(P<0.05),差异均有统计学意义。结论:沐舒坦联合沙丁胺醇雾化吸入治疗慢性支气管炎急性发作患者有较好的临床效果,能有效改善通气状况,提高患者生活质量,值得临床推广应用。
Objective: To observe the clinical effect of mucosolvan combined with salbutamol inhalation in the treatment of acute episode of chronic bronchitis. Methods: A total of 120 patients with acute exacerbation of chronic bronchitis were selected as study subjects and randomly divided into observation group (60 cases) and control group (60 cases). The two groups were given conventional treatment, on this basis, the control group was given inhalation of salbutamol inhalation, the observation group was given salbutamol salbutamol inhalation inhalation therapy, 7 days for a course of treatment after treatment was observed and compared the clinical efficacy of the two groups, Arterial blood gas analysis results, ventilation function to improve the situation. Results: After treatment, the symptoms of both groups were improved. The total effective rate (80.0%) in the observation group was significantly higher than that in the control group (60.0%), the difference was statistically significant (P <0.05) , Sputum, asthma symptoms were significantly improved (P <0.05), dyspnea symptom improvement compared with no significant difference (P> 0.05), but the observation group improved more significantly than the control group; observation group 1 second (P <0.05). The improvement of ventilation / blood flow (V / Q) in the observation group was significantly better than that of the control group (P <0.05), the differences were statistically significant significance. Conclusion: Mucosolvan combined with salbutamol inhalation for the treatment of patients with acute exacerbation of chronic bronchitis has a good clinical effect, which can effectively improve ventilation and improve the quality of life of patients, and is worthy of clinical application.