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我们自1983年3月以来用多抗甲素治疗再生障碍性贫血5例,白细胞减少症6例,均获得了显著效果,现将治疗结果小结如下。 材料与方法 一、一般资料:5例再生障碍性贫血,原发性4例,继发性1例(继发于马利兰),均为慢性型。符合1981年4月廊坊会议制定的再生障碍性贫血诊断标准。男性2例,女性3例。年龄最小为20岁,最大50岁。入院前病程最短为1月,最长5年。治疗前血红蛋白(Hb)最低为3.1克,最高7.0克;白细胞(WBC)最低500,最高2500;血小板最低1.8万,最高7.0万。骨髓象除1例增生活跃外(但巨核细胞少,非造血细胞多),其余4例均为增生减低。1例系初治,4例均有经其他药物(如丙酸睾丸酮,康力龙、士的年、强的松和中药等)治疗无效史。
We since March 1983 with poly acitretin treatment of aplastic anemia in 5 cases, leukopenia in 6 cases, have achieved significant results, the treatment results are summarized below. Materials and Methods First, the general information: 5 cases of aplastic anemia, primary in 4 cases, secondary in 1 case (secondary to Maryland), are chronic type. Meet the diagnosis of aplastic anemia developed in Langchuang meeting in April 1981. 2 males and 3 females. The youngest is 20 years old and the oldest is 50 years old. The shortest course of admission before January is 1 month, the longest 5 years. Before treatment, hemoglobin (Hb) minimum of 3.1 grams, the highest 7.0 grams; white blood cells (WBC) minimum 500, the highest 2500; platelet minimum 18,000, up to 70,000. In addition to one case of bone marrow hyperplasia outside the active (but fewer megakaryocytes, non-hematopoietic cells), the remaining 4 cases were reduced proliferation. One case was untreated, and the other 4 cases had history of ineffective treatment by other drugs (such as testosterone propionate, quetiapine, sevoflurane, prednisone and traditional Chinese medicine).