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[目的 ]探讨乙型肝炎表面抗原阳性肝硬变的特点 .[方法 ]检测 2 2 0例乙型肝炎表面抗原阳性肝硬变患者乙型肝炎病毒标志物及乙型肝炎病毒DNA .[结果 ]乙型肝炎e抗原缺失者 148例 ,占 6 7% ,乙型肝炎e抗原阳性者 72例 ,占32 % .乙型肝炎e抗原缺失者乙型肝炎病毒DNA阳性率为 5 9% (77例 ) ,乙型肝炎e抗原阳性者为 40 % (5 3例 ) .乙型肝炎表面抗原、乙型肝炎核心抗体阳性感染模式出现率最高 ,为 38% .[结论 ]乙型肝炎表面抗原阳性肝硬变化患者e抗原缺失者居多 ,且病毒复制明显 .
[Objective] To investigate the characteristics of hepatitis B surface antigen-positive cirrhotic patients. [Methods] The detection of hepatitis B virus markers and hepatitis B virus DNA in 220 patients with hepatitis B surface antigen-positive cirrhosis. [Results] 148 cases of hepatitis B e antigen deletion accounted for 67%, 72 cases of hepatitis B e antigen positive, accounting for 32% .The hepatitis B e antigen deletion hepatitis B virus DNA positive rate was 59% (77 cases ), Hepatitis B e antigen was 40% (53 cases) .The positive rate of hepatitis B surface antigen and hepatitis B core antibody positive infection was the highest, 38%. [Conclusion] Hepatitis B surface antigen positive liver Patients with hard e antigen deletion were mostly, and the virus replication was obvious.