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以 5 - (S) - (d-氧基 ) - 2 (5 H) -呋喃酮为起始原料 ,对具有肝保护活性的天然产物goodyeroside A进行了全合成研究。将合成所得目标产物的比旋光值及光谱数据与天然产物的数值相比较 ,两者一致 ,证明两者的结构与构型相同。
A total synthesis study of goodyeroside A, a natural product with hepatoprotective activity, was carried out starting from 5 - (S) - (d-hyenceoxy) -2 (5 H) -furanone. The optical rotation and spectral data of the target product obtained by the synthesis are compared with those of natural products, and the two are in agreement. It is proved that the structures and configurations of the two are the same.