《医学世界新闻》第23卷第6期(1982年)报道波士顿消息:淋巴瘤细胞膜的免疫受体可能不仅仅是发生恶性肿瘤的信号,而表明肿瘤的严重性及最终的病程。塔夫茨新英格兰医学中心的肿瘤学家拉德勒斯(Richard A Rudders)说;“临床医师对于积极治疗小细胞淋巴瘤的必要性仍有激烈的争论,我们正在开始区分那些需要有力措施和那些不需要化疗的病人”. Medical World News, Vol. 23, No. 6 (1982) reports from Boston: The immunoreceptors of lymphoma cell membranes may not only signal the occurrence of malignancy, but also indicate the severity and eventual course of the tumor. Richard A Rudders, an oncologist at the Tufts New England Medical Center, said: “There is still a heated debate among clinicians about the need to actively treat small cell lymphoma. We are starting to distinguish between those who need effective measures and Those who do not need chemotherapy.”