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作者分析原发性骨髓增生异常综合征(MDS)患者癌基因表达及其与血细胞形态学、遗传学和临床的关系。130例MDS患者,中数年龄77岁,男75例,女55例。其中,难治性贫血69例,铁粒幼细胞性贫血21例,慢性粒—单核细胞白血病14例,难治性贫血伴幼稚细胞增多24例,难治性贫血伴幼稚细胞增多转化型12例。应用印迹杂交技术和光密度分析,检
The authors analyzed oncogene expression in patients with primary myelodysplastic syndromes (MDS) and its relationship with hemocyte morphology, genetics, and clinical practice. 130 cases of MDS patients, the median age of 77 years, 75 males and 55 females. Among them, there were 69 cases of refractory anemia, 21 cases of subchondral cell anemia, 14 cases of chronic myelomonocytic leukemia, 24 cases of refractory anemia with immature cells, 27 cases of refractory anemia with immature cells increased type 12 example. Application of blot hybridization and optical density analysis, seizure