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目的:探讨BR-TRG-I型体腔热灌注治疗仪实施膀胱内温热灌注化疗治疗高复发表浅性膀胱移行细胞癌的效果。方法:选取2011年3月~2014年10月收治的高复发表浅性膀胱移行细胞癌患者90例,随机分为研究组(n=45)和对照组(n=45)。对照组患者术后24小时内行膀胱灌注,研究组患者术后3天行丝裂霉素膀胱腔内热灌注化疗。结果:研究组患者膀胱局部复发率为33.3%(15/45),显著低于对照组的77.8%(35/45)(P<0.05);复发时间和复发间期均显著长于对照组(P<0.05);复发肿瘤个数显著少于对照组(P<0.05)。结论:BR-TRG-I型体腔热灌注治疗仪实施膀胱内温热灌注化疗治疗高复发表浅性膀胱移行细胞癌患者效果显著,值得在临床推广。
Objective: To investigate the effect of BR-TRG-I intraluminal hyperthermic perfusion therapy device on intravesical hyperthermic perfusion chemotherapy in the treatment of high recurrence superficial bladder transitional cell carcinoma. METHODS: Ninety patients with highly recurrent superficial bladder transitional cell carcinoma who were admitted to our hospital from March 2011 to October 2014 were randomly divided into study group (n = 45) and control group (n = 45). Patients in the control group underwent intravesical instillation within 24 hours after operation. Patients in the study group received intravesical intravesical instillation of mitomycin 3 days after the operation. Results: The local bladder recurrence rate was 33.3% (15/45) in study group, which was significantly lower than 77.8% (35/45) in control group (P <0.05). The recurrence time and recurrence interval were significantly longer in the study group than in the control group <0.05). The number of recurrent tumors was significantly less than that of the control group (P <0.05). Conclusion: BR-TRG-I intraluminal hyperthermic perfusion therapeutic apparatus with intravesical hyperthermic perfusion chemotherapy is effective in treating patients with highly recurrent superficial bladder transitional cell carcinoma and is worthy of clinical promotion.