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自麻疹疫苗应用以来,麻疹的发病率和死亡率虽然得到有效控制,但在麻疹疫苗接种率较高的局部地区仍经常发生麻疹的散发和暴发、流行.为探讨本地区实施计划免疫后麻疹的流行规律,对1990～1997年的有关资料做如下分析:1 材料和方法1.1 资料来源于1990～1997年麻疹疫情报告、流行病学个案调查、血清学资料和年终报表.1.2 免疫监测1990～1997年对8月龄儿童麻疹初免前及初免后1个月测定麻疹抗体阳转率,采用分层整群抽样方法,对健康人群453人进行检测.用酶联免疫吸附试验(ELISA)检测麻疹抗体,以≥1:200为阳性,≥1:800为保护水平.
Although the incidence and mortality of measles have been effectively controlled since the application of measles vaccine, measles distribution and outbreaks are still frequent in some areas with high measles vaccination rates.To investigate the impact of measles Epidemiology of the relevant data from 1990 to 1997 to do the following analysis: 1 Materials and methods 1.1 Data from 1990 to 1997 measles epidemic report, epidemiological case studies, serological data and year-end reports .1.2 immune monitoring 1990 ~ 1997 Measles antibody positive rate was measured before measles immunization and at 1 month after the first immunization in 8-month-old children, and 453 healthy people were detected by stratified cluster sampling method.Using enzyme linked immunosorbent assay (ELISA) Measles antibody, ≥ 1: 200 as a positive, ≥ 1: 800 for the protection level.