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目的 探讨经内镜球囊扩张术治疗贲门失弛缓症的疗效和安全性。方法 经内 镜应用单、双食管球囊扩张导管扩张，术后定期随访和检查，观察患者临床症状缓解与复发 、内镜和 X线钡餐检查结果。结果 43例患者治疗后吞咽困难症状都得到缓解，患者有贲门 粘膜撕裂、擦伤、渗血等，未发生穿孔、呕血或黑便等并发症。随访时间 3个月～ 4.8年， 平均 2.6年。治疗后 1/2、 1、 2、 3年症状缓解率依次为 90.7％ (39/43)、 85.3％ (29 /34)、 82.6％ (19/23)、 82.4％ (14/17)，症状复发率依次为 9.3％ (4/43)、 14.7％ ( 5/34)、 17.4％ (4/23)、 17.6％ (3/17)。此外，随访出现反酸 16例 (37.2％ )、烧心 1 3例 (30.2％ )，诊断Ⅰ期反流性食管炎 6例 (14.0％ )。结论 经内镜球囊扩张术治疗贲 门失弛缓症在近期或远期疗效都比较满意，也比较安全。
Objective To investigate the efficacy and safety of endoscopic balloon dilatation in the treatment of achalasia. Methods Endoscopic single and double esophageal balloon dilation catheter dilation, regular follow-up and examination after surgery to observe the clinical symptoms of patients with remission, endoscopy and X-ray barium meal examination results. Results The symptoms of dysphagia in 43 patients were relieved after treatment. The patients had gastric mucosa tear, abrasion, oozing and so on. No perforation, vomiting or melena and other complications occurred. Follow-up time of 3 months to 4.8 years, an average of 2.6 years. The rates of symptom remission after 1, 2, 3 years were 90.7% (39/43), 85.3% (29/34), 82.6% (19/23), 82.4% (14/17) The recurrence rates were 9.3% (4/43), 14.7% (5/34), 17.4% (4/23) and 17.6% (3/17), respectively. In addition, there were 16 cases (37.2%) of acid reflux, 13 cases (30.2%) of heartburn and 6 cases of reflux esophagitis (14.0%). Conclusion Endoscopic balloon dilation in the treatment of achalasia in the near future or long-term efficacy are more satisfactory, but also relatively safe.