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本文报道白术、苍术及其三个组方补中益气丸、四君子汤、枳术丸对离体家兔小肠运动的影响。结果显示以上各单味药及其组方均有明显的抗副交感神经介质乙酰胆碱(ACh)引起的肠痉挛,其中白术在一定程度上尚能对抗交感神经介质肾上腺素(Adr)引起的肠肌麻痹。补脾阳药物对植物神经系统调节的双向影响,可从一个侧面阐明中医调理脾胃的药理学基础。
This paper reports the effects of Atractylodes Rhizome, Atractylodes Rhizome and three groups of Buzhong Yiqi Pills, Sijunzi Decoction and Qizhu Pills on isolated small intestine movements in rabbits. The results showed that each of the above single-drugs and their constituents had obvious anti-intestinal paralysis due to acetylcholine (ACh)-induced intestinal fistula, and Atractylodes macrocephalus was still able to resist the sympathetic nervous system adrenal (Adr)-induced intestinal muscle paralysis to some extent. . The two-way effect of supplementing spleen-yang drugs on the regulation of the autonomic nervous system can clarify the pharmacological basis of TCM treatment of spleen and stomach.