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目的胃大肠癌循环癌细胞的检测。方法用常规细胞学(HE)和免疫细胞化学(ICC)方法对23例进展期胃、大肠癌切除患者门静脉系血及外周血进行癌细胞的检测。结果 23例患者中常规 HE 染色,阳性2例(8.7%),可疑3例(13%);免疫细胞化学方法,阳性4例(17.4%)。4例阳性患者血中癌细胞浓度在40-1000个/ml 范围内。结论循环癌细胞的检测可能有助于预测肝内微转移灶的发生,判断患者预后,为术后选择辅助治疗提供依据。
Objective To detect the colorectal cancer cells. METHODS: Conventional cytology (HE) and immunocytochemistry (ICC) methods were used to detect cancer cells in the portal vein and blood of 23 patients with advanced gastric and colon cancer resection. Results Conventional HE staining was performed in 23 patients, positive in 2 patients (8.7%), suspicious in 3 patients (13%), immunocytochemistry, and positive in 4 patients (17.4%). Four cases of positive patients had blood cancer cells in the range of 40-1000 cells/ml. Conclusion The detection of circulating cancer cells may help to predict the occurrence of intrahepatic micrometastasis, determine the prognosis of patients, and provide basis for selecting adjuvant therapy after surgery.