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介入微波热凝固疗法（invasive microwave coagulation,IMC）是一种新发展起来的治疗肝癌的方法.具体讨论了恒功率IMC疗法.对交替相控加热方式和一种大血管传热模型进行了三维的有限元模拟.目的在于研究:1）介入微波交替相控加热的降低凝固区峰值温度和减小“过热区”大小的效能（有时峰值温度可高达140℃）;2）模拟了大血管的生物传热模型,以研究在IMC治疗中大血管对周围组织传热和热凝固区形态的影响.并且将模拟结果和相应的活体猪实验结果进行对比.研究的结果包括:（1）交替相控加热方式能有效地降低凝固区的峰值温度,并能缩小“过热区”的大小,提高治疗的安全性;（2）由于大血管冷却而造成的“过冷区”热量损失很大,解释了为什么临床中在对靠近大血管的肿瘤进行IMC治疗前实施肝大血管阻断术是一种实用的方法;（3）提出了大血管影响半径（Rev）参数,为临床上进行大血管阻断术提供了理论依据.
Interventional microwave coagulation therapy (IMC) is a newly developed method for the treatment of liver cancer.It discusses in detail the IMC therapy with constant power.The three-dimensional The purpose of this paper is to study: 1) the effect of decreasing the peak temperature in the coagulation zone and decreasing the size of the “overheated zone” (sometimes the peak temperature may reach as high as 140 ℃) by alternating phase-controlled heating; 2) Heat transfer model to study the effects of macrovascular on the heat transfer and thermocoagulation patterns of peripheral tissues during IMC treatment.Meanwhile, the simulation results were compared with those of live pigs.The results of the study include: (1) Alternating phase control Heating method can effectively reduce the peak temperature in the coagulation zone, and can reduce the size of the “overheated zone” to improve the safety of treatment; (2) due to large blood vessels cooling caused by the " Why clinical implementation of large-vessel occlusion of the liver prior to IMC treatment of tumors adjacent to large vessels is a practical approach; (3) Proposes a large vascular influence radius (Re v) parameters, provide a theoretical basis for clinical large blood vessel occlusion.