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目的:分析高龄急性心肌梗死患者应用尿激酶静脉溶栓治疗的效果。方法:随机选择2015年5月至2016年5月在广东同江医院接受治疗的高龄急性心肌梗死患者120例,随机平均分成两组,对照组实施常规治疗,观察组另外进行尿激酶静脉溶栓治疗,比较两组效果。结果:观察组尿激酶溶栓治疗的再通率、不良反应发生率为63.33%、6.67%,对照组为26.67%、18.33%;观察组治疗后肌酐激酶同工酶MB(CK-MB)以及血清肌酐激酶(CK)水平高于对照组;观察组发病后0~2 h接受治疗的再通率为82.76%,3~6 h为55.56%,7~12 h为30.77%。结论:尿激酶静脉溶栓治疗高龄急性心肌梗死能够提高再通率,减少不良反应。
Objective: To analyze the effect of intravenous thrombolysis with urokinase in elderly patients with acute myocardial infarction. Methods: A total of 120 elderly patients with acute myocardial infarction who were treated in Guangdong Tongjiang Hospital from May 2015 to May 2016 were randomly divided into two groups randomly. Patients in the control group received conventional therapy. The patients in the observation group received intravenous infusion of urokinase Treatment, the two groups were compared. Results: The recanalization rate of urokinase thrombolytic therapy in the observation group was 63.33% and 6.67% respectively, which was 26.67% and 18.33% in the control group. CK-MB and CK- Serum creatinine kinase (CK) level was higher than that of the control group. The recanalization rate of the observation group was 82.76% at 0 ~ 2 h, 55.56% at 3 ~ 6 h and 30.77% at 7 ~ 12 h. Conclusion: Intravenous thrombolysis of urokinase in elderly acute myocardial infarction can improve the recanalization rate and reduce adverse reactions.