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目的分析总结2009年3—4月广东省麻疹疫苗(MV)强化免疫活动的有关数据,为制定达到消除麻疹目标策略提供依据。方法该次强化免疫对象为广东省内8月龄至14周岁儿童(包括流动儿童),无论既往有无接种史或患病史,1个月内均接种1剂次麻疹疫苗。通过收集整理广东省MV强化免疫报表数据和现场评估等情况,采用流行病学方法进行分析。结果全省摸底登记8月龄至14周岁儿童共20 437 255人,报告接种数为19 952 519人,报告接种率为97.63%,强化免疫活动前麻疹疫苗调查接种率为71.66%,与强化免疫活动后调查接种率(98.10%)比较,差异有统计学意义(P<0.01)。活动前儿童家长知晓率为91.86%,活动后期知晓率为98.48%,差异有统计学意义(P<0.01);麻疹疫苗强化免疫疑似预防接种异常反应报告发生率为4.21/10万;麻疹疫苗强化免疫后,2009年5—12月麻疹发病数较去年同期下降92.59%,麻疹发病率从2008年的16.10/10万下降到2009年的2.22/10万。结论麻疹疫苗强化免疫是控制和消除麻疹的有效措施,政府主导、多部门配合、声势浩大的宣传发动和良好的组织实施是强化免疫成功的关键。
Objective To analyze and summarize the relevant data of measles vaccine (MV) intensified immunization activities in Guangdong from March to April in 2009, and provide the basis for formulating the strategy of eliminating measles. Methods The intensive immunization was conducted in children aged 8 months to 14 years (including migrant children) in Guangdong Province. One measles vaccine was administered within one month regardless of previous history of vaccination or illness. Through the collection and sorting of MV data and field assessment of MV in Guangdong province, the epidemiological method was used to analyze the data. Results A total of 20 437 255 children aged 8 months to 14 years were enrolled in the province. The number of reported vaccinations was 19 952 519 and the reported vaccination rate was 97.63%. The measles vaccination rate before intensive immunization was 71.66% Survey after the activity of vaccination rate (98.10%), the difference was statistically significant (P <0.01). The awareness rate of children with pre-event immunization was 91.86% and the rate of late-stage awareness was 98.48%, the difference was statistically significant (P <0.01). The incidence rate of measles vaccine immunization vaccination abnormality was 4.21 / After immunization, the incidence of measles in May-December 2009 dropped by 92.59% over the same period of last year. The incidence of measles dropped from 16.10 / 100000 in 2008 to 2.22 / 100000 in 2009. Conclusion The measles vaccine boosting is an effective measure to control and eliminate measles. Government-led, multisectoral cooperation, vigorous advocacy and good organizational implementation are the keys to successful immunization.