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目的探讨本地区维吾尔族(维族)胃癌的病因、发病情况、临床表现、胃镜和病理特点。方法前瞻性研究分析2005年6月-2007年7月在我院行电子胃镜检查并取活检病理确诊胃癌的患者105例,制定检测幽门螺杆菌(HP)感染的科研诊断标准:即14C-尿素呼气试验和HP抗体试验检测均阳性,并对相关病因、发病情况、临床表现、胃镜、病理检查结果进行登记。结果本地区胃癌的致病因素中HP感染率为27.6%,有吸烟和/或饮酒者占62.2%,男性明显多于女性,男女比例6∶1,41-60岁为高发年龄段占67.6%,职业以农民占多数占86.7%,临床报警症状主要是上消化道出血、贫血、体重下降、吞咽受阻,病人就诊较晚,平均病程>6个月,均为进展期胃癌,以胃体部多发占48.6%,以溃疡浸润型多见占59%,病理分型以腺癌为主占83.8%。结论本地区胃癌患者HP感染率低,提示HP感染可能不是胃癌的主要病因,而烟、酒、饮食、环境可能是主要病因。对41-60岁年龄段,尤其是男性,农民出现报警症状,胃镜检查发现胃体部病变如溃疡、糜烂等病灶,应警惕胃癌,多取活检进一步确诊。
Objective To investigate the etiology, morbidity, clinical manifestations, gastroscope and pathological features of Uygur (Uygur) gastric cancer in this area. Methods A prospective study of 105 patients with gastric cancer diagnosed by gastroscopy and biopsy in our hospital from June 2005 to July 2007 was conducted to establish the scientific diagnostic criteria for detecting Helicobacter pylori (HP) infection: 14C-urea Breath test and HP antibody test were positive, and related etiology, incidence, clinical manifestations, gastroscopy, pathological examination results were registered. Results The prevalence of gastric cancer in this area was 27.6% for HP, 62.2% for smoking and / or drinking, significantly more men than women, 6:1 for men and women, and 67.6% for those aged 60-60 years. , Occupations accounted for the majority of farmers accounted for 86.7%, the clinical symptoms of the alarm is mainly upper gastrointestinal bleeding, anemia, weight loss, swallowing obstruction, the patient was treated later, the average duration of> 6 months, are advanced gastric cancer, Occurred in 48.6%, ulcer infiltration more common 59%, pathological type of adenocarcinoma accounted for 83.8%. Conclusion The prevalence of HP infection in patients with gastric cancer is low in this region, suggesting that HP infection may not be the main cause of gastric cancer. However, smoking, alcohol, diet and environment may be the main causes. 41-60 years of age, especially men, farmers alarm symptoms, gastroscopy found body lesions such as ulcers, erosion and other lesions should be alert to gastric cancer, and more biopsy for further diagnosis.