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避孕药与癫痫:癫痫病人服用避孕药是否安全,多年来已有所关注。有人研究了血中激素水平与改变大脑兴奋性之间的关系。1981Gowers注意到在月经期癫痫发作增加。其后研究揭示了雌激素可降低发作而孕激素可提高发作阈;在月经周期中,发作最多的是在雌激素高峰于排卵期及孕酮急剧下降的经前期与经期之间。这说明雌、孕激素能影响癫痫发作。Espir等用对照交叉观察,对20例癫痫妇女在常规进行抗癫痫治疗期服
Contraceptives and epilepsy: Epilepsy patients taking birth control pills are safe, over the years have been concerned about. It has been studied the relationship between blood hormone levels and changes in brain excitability. 1981Gowers noticed an increase in seizures during menstruation. Subsequent studies revealed that estrogen may reduce seizures and progestins may increase the seizure threshold; in the menstrual cycle, seizures most frequently occur between the premenstrual and menstrual periods during which estrogen peaks during ovulation and when progesterone falls sharply. This shows that estrogen and progestin can affect seizures. Espir and other control cross observation, 20 cases of epilepsy women in the conventional anti-epileptic treatment period