论文部分内容阅读
采用静豚注射四碘四氯荧光素二钠，以波长为５５０±２０ｎｍ的光照射耳蜗的方法，诱导耳蜗局部微血管内发生光化学反应；电镜观察见血管内皮细胞受损，以致血小板被受损的内皮细胞激活，粘附聚集于内皮细胞或暴露的基膜表面而形成微血栓，导致耳蜗发生微循环障碍。微血栓由脱颗粒和含颗粒、形态不规则的血小板构成，其间有少量纤维素和部分红细胞。提示：光化学反应致血栓形成过程与病理状态下的内皮细胞受损和基膜暴露激活血小板致血栓形成的过程基本一致，与临床某些内耳微循环障碍的病理过程可能有一定的相似性。
Using intravenous infusion of IV tetrachlorofluorescein disodium, irradiation of cochlea with wavelength of 550 ± 20nm induced photochemical reaction in local capillaries of the cochlea. Electron microscopy showed that endothelial cells were impaired, resulting in impaired platelets Endothelial cells activate, adhere to the surface of endothelial cells or exposed basement membrane formation of micro-thrombus, leading to microcirculation of the cochlea. Micro-thrombi consist of degranulated and granule-containing, irregularly shaped platelets with a small amount of cellulose and some red blood cells in between. It is concluded that the process of thrombosis induced by photochemical reaction is basically the same with the damage of endothelial cells under pathological conditions and the thrombosis caused by platelet activation and platelet activation, which may be similar to the pathological process of some microcirculation disorders in the inner ear.