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本研究在培养的兔胸主动脉血管平滑肌细胞上 ,观察了丝裂素活化蛋白激酶 (ｍｉｔｏｇｅｎ ａｃｔｉｖａｔｅｄｐｒｏｔｅｉｎｋｉｎａｓｅｓ ,ＭＡＰＫ)在内皮素促血管平滑肌细胞增生中的作用。发现内皮素 1呈时间和浓度依赖性地促进细胞摄取3Ｈ ＴｄＲ和激活ＭＡＰＫ ,此作用?
In this study, we observed the effect of mitogen activated protein kinases (MAPK) on the proliferation of vascular smooth muscle cells induced by endothelin in cultured rabbit aortic vascular smooth muscle cells. Endothelin 1 was found in a time and concentration-dependent manner to promote cellular uptake of 3H TdR and activation of MAPK, this effect?