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目的:评估马来西亚东西部三级医院感染性角膜炎流行病学及发病因素。方法:收集来自马来西亚西部Sungai Buloh医院、吉隆坡综合医院和东部Queen Elizabeth医院、沙捞越州综合医院的感染性角膜炎患者207例。研究记录了危险因素。进行角膜刮片镜检和培养。结果:马来西亚西部感染性角膜炎最普遍的风险因素是植物性损伤(28.5%)和非植物性损伤(18.3%)。27.7%的创伤病例与工作有关,其中外籍男性工作者占34.2%。马来西亚东部最普遍的风险因素是配戴隐形眼镜(32.9%)。马来西亚东西部绿脓假单胞菌是感染性角膜炎最常见的病菌。马来西亚西部最常见的真菌病原体是镰刀菌,占所有阳性真菌培养物的60%。结论:马来西亚东西部公立医院细菌性角膜炎检出率较高,而东部隐形眼镜配戴则是常见风险因素(P<0.05),西部真菌性角膜炎检出率高。
Objective: To evaluate the epidemiology and pathogenesis of infectious keratitis in tertiary hospitals in eastern and western Malaysia. Methods: A total of 207 patients with infectious keratitis from Sungai Buloh Hospital, Kuala Lumpur General Hospital and western Queen Elizabeth Hospital and Sarawak General Hospital in western Malaysia were collected. The study documents the risk factors. Corneal scraping microscopy and culture. Results: The most common risk factors for infectious keratitis in western Malaysia were plant injury (28.5%) and non-plant injury (18.3%). 27.7% of traumatic cases related to work, of which foreign male workers accounted for 34.2%. The most common risk factor in eastern Malaysia is wearing contact lenses (32.9%). Pseudomonas aeruginosa is the most common infectious keratitis in Malaysia. The most common fungal pathogen in western Malaysia is Fusarium, which accounts for 60% of all positive fungal cultures. Conclusion: The detection rate of bacterial keratitis in public hospitals in eastern and western Malaysia is higher than that in eastern contact lenses (P <0.05). The detection rate of western fungal keratitis is high.