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本研究利用高输入阻抗微电极放大器，观察正常豚鼠（ｎ＝３５）前庭壶腹嵴内电位（ＡＥＰ），以及缺氧、缺血、静脉注射速尿对其影响，探讨ＡＥＰ的电生理特性。结果表明正常豚鼠ＡＥＰ为４．５５±１．３５ｍＶ，停止呼吸机２ｍｉｎ，ＡＥＰ下降至２．３±０．８ｍＶ，恢复呼吸后均可观察到超射现象，阻断升主动脉后ＡＥＰ持续下降，达最大负值为－１９．４±１．７ｍＶ，所需时间为５２．５±９．６ｍｉｎ，约１５０ｍｉｎ后缓慢上升至０。静脉注射速尿后与注射前无显著差异。支持ＡＥＰ是不同于耳蜗内电位的正电位，有不同于耳蜗内电位的电生理特性。就其在前庭生理研究中的应用前景进行讨论
In this study, using high input impedance microelectrode amplifier to observe the normal guinea pig (n = 35) vestibular amputation potential (AEP), as well as hypoxia, ischemia, intravenous furosemide on its impact on electrophysiological characteristics of AEP. The results showed that the AEP of normal guinea pig was 4.55 ± 1.35mV, the respirator was stopped for 2min, the AEP decreased to 2.3 ± 0.8mV, and the over shoot phenomenon could be observed after resuscitation, and the AEP continued to decline after blocking the ascending aorta , Reaching a maximum negative value of -19.4 ± 1.7mV, the time required for 52.5 ± 9.6min, slowly rose to 0 after about 150min. Intravenous furosemide after injection and no significant difference. Support AEP is a positive potential different from that of the cochlear potential, and has a different electrophysiological property from that of the cochlear potential. Discuss its application prospects in vestibular physiology research