论文部分内容阅读
研究药物反应与遗传关系的一门科学称药物遗传学。引起药物不良反应的因素很多,诸如年龄,性别,病理和外界环境因素等,但遗传因素往往起着决定性作用。遗传因素怎样导致药物不良反应的产生,这是本文所要阐述的基本问题,分为下列几方面加以简单介绍。(一)药物反应类型群体试验表明药物反应表现出很大的个体差异性。反应曲线的分布可呈连续性的(即单顶型)和非连续性(双顶式三
A science that studies the relationship between drug reactions and inheritance is called pharmacogenomics. Adverse reactions caused by many factors, such as age, gender, pathology and environmental factors such as environmental factors, but genetic factors often play a decisive role. How genetic factors lead to the emergence of adverse drug reactions, which is the basic problem to be elaborated in this article, is divided into the following aspects to be briefly introduced. (A) the type of drug reactions Group tests showed that drug reactions showed a great individual differences. The distribution of the reaction curve can be continuous (ie, single-top) and non-continuous (double top three