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目的探讨尼莫地平治疗急性脑梗死的疗效及安全性。方法将100例经CT或MRI确诊的急性梗死患者随机分为两组:治疗组(60例)用尼莫地平注射液10mg加入0.9%氯化钠注射液500ml中静脉缓慢滴注(5～7h滴完),qd,共14天。并以对照组(40例)用丹参注射液20ml加入5%低分子右旋糖酐注射液500ml中静脉滴注,qd,共14天对照研究。结果治疗组显效率为70%,有效率为86.7%,对照组显效率为32.5%,有效率为70%,两组间有显著差异(P<0.01)。结论尼莫地平对治疗急性脑梗死有较好的疗效。
Objective To investigate the efficacy and safety of nimodipine in the treatment of acute cerebral infarction. Methods One hundred patients with acute infarction diagnosed by CT or MRI were randomly divided into two groups: the treatment group (n = 60) was treated with nimodipine injection (10mg), 0.9% sodium chloride injection (500ml) Drip finished), qd, a total of 14 days. The control group (40 cases) was treated with Danshen injection 20ml by adding 5% low molecular weight dextran injection 500ml intravenously, qd for 14 days. Results In the treatment group, the effective rate was 70%, the effective rate was 86.7%, the effective rate was 32.5% and the effective rate was 70% in the control group. There was significant difference between the two groups (P <0.01). Conclusion Nimodipine is effective in treating acute cerebral infarction.