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冠状动脉血流储备是临床评价冠脉循环能力的重要指标之一,既往多采用介入性方法进行测定。本研究应用经胸超声心动图冠脉血流显像新技术观察17例正常成人静脉内注射潘生丁结合等长握力应激状态下心外膜冠脉血流的变化,结果显示最大血流变化出现在实验开始后第4~5分钟,峰值血流速度比3.771±0.812,舒张期峰速积分比为3.529±0.041。全部受试者无明显不良反应。表明冠状动脉血流显像新技术结合潘生丁握力实验是一可行的无创性评价正常冠脉血流储备的新方法。
Coronary flow reserve is one of the most important indexes for clinical evaluation of coronary circulation. In the past, the interventional method was used to determine coronary flow. In this study, transthoracic echocardiography coronary flow imaging was used to observe the change of epicardial coronary flow in 17 normal adults treated with dipyridamole and isopentenyltransferase. The results showed that the maximum blood flow changes occurred in The first 4 to 5 minutes after the start of the experiment, peak blood flow velocity ratio of 3.771 ± 0.812, diastolic peak velocity integral ratio of 3.529 ± 0.041. All subjects without significant adverse reactions. The results show that coronary angiography combined with dipyridamole grip force test is a feasible and noninvasive method to evaluate normal coronary flow reserve.