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国外学者曾用吸入低氧混合气体和把动物送入高原的方法研究过急性和慢性缺氧对肺动脉压影响,而国内对这方面工作研究较少。本文观察不同种的平原动物在不同摸拟高原和世居高原动物的肺动脉压和血气变化并寻找降低肺动脉压的药物。 18只雄性平原狗,体重为11～15公斤。12只雄性高原世居狗(3865m),体重为10～17公斤。11只平原雄性猪,体重20～49.5公斤。4只高原世居猪(3658m),体重30～40公斤,在麻醉下进行右心导管,以水检压计测定肺动脉压和肺动脉楔压。高
Foreign scholars have used inhalation of hypoxia mixed gas and the animal into the plateau method of acute and chronic hypoxia on the impact of pulmonary hypertension, and domestic research on this area less. This article observed different kinds of plains animals in different simulated plateau and native plateau animals, pulmonary arterial pressure and blood gas changes and looking for drugs to reduce pulmonary artery pressure. 18 male plain dogs, weighing 11 to 15 kg. 12 male highland dogs (3865m), weighing 10 to 17 kg. Eleven plain male pigs, weighing 20 to 49.5 kg. Four highland native pigs (3658m), weighing 30-40 kg, underwent right cardiac catheterization under anesthesia, and pulmonary arterial pressure and pulmonary wedge pressure were measured with a water checker. high