氯氮平致癫痫发作居众抗精神病药之首,现将我院1994～1996年住院期间氯氮平所致癫痫发作24例报告如下: 一 一般资料 氯氮平致癫痫发作24例中,男13例,女11例,年龄15～55岁,平均36.8岁。精神分裂症21例,情感性精神障碍3例。既往有脑外伤、脑炎史2例。 二 服药剂量、时间与癫痫发作的关系 所有患者用药量均从50～100mg/日开始,癫痫发作时药量100～600mg/日,平均450mg/日。其中100 Clozapine seizures caused by the majority of people living with antipsychotic drugs, now in our hospital during 1994 to 1996, 24 cases of seizures caused by clozapine reported as follows: a general information of 24 cases of seizures caused by clozapine, male 13 cases, 11 females, aged 15 to 55 years, an average of 36.8 years old. Schizophrenia in 21 cases, 3 cases of emotional disorders. Past traumatic brain injury, encephalitis in 2 cases. Second, the dose of medication, the relationship between time and seizures All patients medication dose from 50 ~ 100mg / day, the dose of seizures 100 ~ 600mg / day, an average of 450mg / day. 100 of them