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测定907例次孕各期正常孕妇空腹晨尿钙(Ca),羟脯氨酸(Hyp),肌酐(Cr),并计算各孕周,各孕月.各孕期之Ca/Cr、Hyp/Cr之平均值,结果为Ca/Cr值自早孕以后逐渐增加,高峰为孕8月,然后逐渐下降至孕41周与对照组相近。Hyp/Cr值由早孕之后逐渐上升,直至孕10月为高峰,41周略有下降。提示妊娠期随胎儿成长发育的不同时期从母体摄钙增加的程度不同,孕中晚期摄钙最多,母体骨钙释出量最大,骨代谢、骨胶原分解最强,胎儿成熟即将分娩之时有所减弱。
The calcium, hydroxyproline (Hyp) and creatinine (Cr) of 907 pregnant women of the second trimester were measured, and the gestational age, The results showed that the Ca / Cr value increased gradually from the first trimester to the peak of the first trimester, then gradually decreased to the fourth trimester, which was similar to the control group. The Hyp / Cr value increased gradually from the first trimester till the peak in the third trimester, and slightly decreased in the fourth week. Prompted gestational growth and development at different stages of fetal growth at different stages of calcium intake from the maternal different degrees of increase in the second trimester of pregnant women up to calcium, maternal calcium release the largest amount of bone metabolism, the strongest decomposition of collagen, the fetus is about the time of delivery Weakened.