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目的:本次实验的主旨在于研究不同方式的营养供给途径对于机械通气患者的营养摄入和免疫的不同作用。方法:随机选取2013年7月到2014年12月入住我院重症监护病房(icu)的机械通气患者48例,将其分为两组,随机分为全肠外营养(TPN)组和肠内营养(EN)组,同时观察两组患者在营养支持前和营养支持后十天各指标变化,其中指标包括各类影响,免疫球蛋白,机械通气时间以及各类并发症等,之后对这些指标进行统计分析,以发现这两种营养供给方式的区别。结果:十天后EN组患者与治疗前比较血清总蛋白(PT)、ALB、PA和HB水平明显上升(P<0.05),TPN组病人也较治疗前显著性上升(P>0.05);与TPN组比较上述指标显著性上升(P<0.05);EN组免疫指标:IgA、IgM较营养支持前明显升高,与TPN组比较P<0.05;EN组与TPN组比较,机械通气时间缩短,并发症明显降低,均P<0.05。结论:肠内营养支持相比于肠外营养支持更能够加快患者的痊愈,有利于病情的稳定。
Purpose: The purpose of this experiment is to study the different effects of different modes of nutrient supply on nutritional intake and immune responses in patients with mechanical ventilation. Methods: Forty-eight patients with mechanical ventilation admitted to intensive care unit (ICU) in our hospital from July 2013 to December 2014 were randomly divided into two groups and randomly divided into TPN group and enteral (EN) group. At the same time, the changes of each index in two groups before and after nutritional support were observed. The indexes included various kinds of effects, immunoglobulin, mechanical ventilation time, various complications, etc. After that, Conduct statistical analysis to find the difference between the two nutrient supply methods. Results: Ten days later, the levels of serum total protein (PT), ALB, PA and HB in EN group were significantly higher than those before treatment (P <0.05), but also in TPN group (P> 0.05) Compared with TPN group, the levels of IgA and IgM in EN group increased significantly (P <0.05); the duration of mechanical ventilation in EN group was shorter than that in TPN group (P <0.05) Symptoms were significantly lower, both P <0.05. CONCLUSIONS: Enteral nutrition support is more likely to improve patient recovery than parenteral nutrition support and contribute to the stabilization of the condition.