近10年来,已有报告指出伴有或不伴有休克的严重侵袭性链球菌感染病例增多。其明显增加的因素,包括强致病力菌株的传播,患者的免疫系统失控和生活模式诸如群体儿童抚育方式的改变等。 侵袭性感染的过程往往非常凶猛,可以死亡告终,甚至病前健康状况良好的人亦然。虽然人们对此类感染的认识已明显深化,尽管有先进的监护系统、抗生素治疗和积极的外科处理等,但链球菌中毒性休克综合征和坏死性筋膜炎的病死率仍很高。 In the past 10 years, there have been reports of an increased incidence of severe invasive streptococcal infections with or without shock. Significantly increased factors include the spread of virulent strains, uncontrolled patient immune system and lifestyle changes such as changes in the way groups foster childcare. The process of an aggressive infection is often very fierce and can end in death, even for people who are in good health before the illness. Although awareness of such infections has been significantly deepened, the mortality of streptococcal toxic shock syndrome and necrotizing fasciitis remains high despite advanced surveillance systems, antibiotic therapy and aggressive surgical procedures.