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实验结果表明,益母口服液、益母冲剂(28g/kg及3.5g/kg)均可显著拮抗缩宫素所致大鼠子宫痛性痉挛反应,但益母口服液的作用强于益母冲剂,两者在大剂量时出现显著性差异。小鼠离体子宫实验表明两种制剂从0.1ml至0.8ml时均可明显对抗垂体后叶素所致子宫收缩,使子宫平滑肌张力降低,并呈现较好的量效反应关系。子宫平滑肌肌电实验,结果表明,当益母口服液剂量为3.5g/kg时,即可明显减少子宫肌电发放频
The experimental results showed that Yimu Oral Liquid and Yimu Granules (28g/kg and 3.5g/kg) could significantly antagonize the uterine analgesia induced by oxytocin, but the effect of Yimu Oral Liquid was stronger than that of Motherwort. The granules showed significant differences at high doses. The experiment of isolated uterus in mice showed that the two preparations could obviously counteract the uterine contraction induced by pituitrin when the two preparations were from 0.1ml to 0.8ml, and the uterine smooth muscle tension was reduced, and showed a better dose-response relationship. The uterine smooth muscle myoelectricity experiment results show that when the dosage of Yimu oral solution is 3.5g/kg, the frequency of uterine myoelectricity can be significantly reduced.