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目的 观察急慢性酒精中毒后视网膜色素上皮损伤情况。 方法 对 9例 (18眼 )急慢性酒精中毒患者进行了眼底荧光血管造影 (FFA)及视觉电生理 (ERG ,VEP)检查。 结果 2例 (4眼 )急性酒精中毒者经药物治疗后视力完全恢复 ,1例 (2眼 )FFA见双眼底视网膜色素上皮弥漫性损伤。慢性酒精中毒 6例 12眼经药物治疗后FFA为双眼底视网膜色素上皮炎性改变 ,ERG ,VEP无好转。 结论 急性酒精中毒引起的眼部改变大多可恢复 ,慢性酒精中毒则造成视网膜和黄斑不可逆的器质性损害。FFA ,ERG ,VEP检查可以客观地反映酒精中毒后对视网膜色素上皮损害的程度和转归。
Objective To observe the damage of retinal pigment epithelium after acute and chronic alcoholism. Methods Nine patients (18 eyes) with acute or chronic alcoholism underwent fundus fluorescein angiography (FFA) and visual electrophysiology (ERG, VEP). Results Two cases (4 eyes) of acute alcohol poisoning had complete recovery of visual acuity after medication, and one case (2 eyes) of FFA was found to have diffuse damage of bilateral retinal pigment epithelium. 6 cases of chronic alcoholism in 12 eyes after treatment of FFA for bilateral retinal pigment epithelial inflammatory changes, ERG, VEP no improvement. Conclusion Most of the ocular changes caused by acute alcoholism can be recovered. Chronic alcoholism causes irreversible and irreversible damage to the retina and macula. FFA, ERG, VEP examination can objectively reflect the extent and outcome of retinal pigment epithelium damage after alcoholism.